BRT with MEBT/MEBO opens up a new approach to the prevention and treatment of infection. 

Local and systemic infection is a difficult problem of burns treatment and today in the era of multidrug resistant pathogens, we are scarcely further ahead than we were years ago. 

Many antibiotics have been applied but the efficacy proves unsatisfactory. 

BRT with MEBT/MEBO resolves this problem by treating the local area in compliance with the pathogenesis of the infection of burns wound. 

This treatment controls infection of burns wound by changing the ecological environment. 

Concurrently, by applying BRT with MEBT/MEBO to the large-area burns, in accordance with the law of systematic pathogenesis of infections, we discover that BRT with MEBT/MEBO is capable of mobilizing and coordinating the potential physiological energy of the systemic wound stress reaction. 

This alone has successfully advanced a systematic anti-infection principle for treating large-area burns. 

To be more specific: 

At the shock stage, when wound stress reaction is on the upsurge, we recommend the systemic application of broad spectrum antibiotics with no adverse effect on the kidney.

After this stage, when synthetic metabolism of protein begins, we recommend that one stop the application of any antibiotics.

In the whole course of treatment, if systemic infection occurs occasionally, a single large dose of broad-spectrum antibiotic (one with no side effects on kidney) is applied.

In this fashion, BRT with MEBT/MEBO offers a systematic scheme for removing the focus of infection and minimizes the dependence upon antibiotics.