and effects in controlling wound infections of MEBO in treating wounds
Isolate wound, and reduce contamination:
As is well
known, there are two sources of different kinds of wound
is contamination from extraneous sources, mainly including
microorganism invasion in the air and medical pollutions;
contamination from internal source, mainly referring to
infection inside the human body.
Generally, there are about 1000
aerobic bacteria and semi-aerobic bacteria in 1 cm2 of normal skin,
accounting for 1～10% of the total bacteria in the human body.
anaerobic bacteria and semi-anaerobic bacteria in the visceral organs
in the human body, accounting for 90～99% of the total
inside and outside florae are called "normal florae" in non-pathogenic
When the environment and conditions change, there
flora imbalance, resulting in systemic or local infection.
is applied on the wound, its two-layer structure covers the wound
tightly, isolate the environmental pollution, and reduce the invasion
of external bacteria, so as to achieve the objective of isolating wound
and abating pollution.
Unobstructed draining, bacteria removal:
automatic liquid flow circulation in the wound tissues, remove the
bacteria in the wound tissues in the condition of unobstructed
draining, so as to decrease the bacterial concentration in the wound,
control the bacterial infection from inside, relieve or get rid of
systematic and local bacterial infection, and abate the invasion of
anaerobic bacteria and semi-anaerobic bacteria
the existing and reproduction environment of bacteria:
is well known, aerobic bacteria and semi-aerobic bacteria can live and
reproduce well in a humid environment, while anaerobic bacteria and
semi-anaerobic bacteria can live and reproduce well in a humid
environment with no oxygen or little oxygen.
So long as this
condition is destroyed, the bacteria cannot live.
MEBT and MEBO block
the supply of nutrition, water and oxygen which are essential for
bacteria, destroy the existing condition of bacterial by binding MEBO
with the wound necrotic tissues through the lipophilic function of
MEBO, so that various bacteria cannot survive in the wound and the
ointment, and they are removed from the wound through the inducing flow
excretory function of the ointment.
As a result, the local and systemic
bacterial infections are controlled. This method is completely
different from dry therapy: moist
environment is favorable for the
regeneration of tissue cells.
Especially, the regeneration action is
very obvious in the cells impending death.
is harmful for bacteria, so that MEBO has specific
4. Direct or
indirect bactericidal and bacteriostatic
Although the bactericidal effects and the
actions of MEBO are weak, when it is used together with other active
ingredients, such as phellodendron bark ester oil, it has direct
bactericidal effects and bacteriostatic actions, and can reduce
bacteria and control infections.
In total, the manifestation of the anti-infection
effect of MEBO is as
follows: It has important
functions of blocking bacteria, inhibiting
bacteria, removing bacteria, and destroying the existing conditions of
Therefore, MEBT and MEBO have strong capacity in
Although only weak bacteriostatic and
bactericidal effects were observed in the experiments, its powerful
infection control capacity could be proved by the clinical practice.