What is the function of the FIM in wound regenerative reparation?It forms between wound surface and MEBO and allows an osmotic pressure to form in both sides of the membrane; one side is hydrophilic (wound tissue side) and the other side is lipophilic (MEBO side). Exchanges of materials as ions are taking place, so that the metabolism products of the wounds can be excreted outside of the membrane by osmosis. Through the same mechanism, the MEBO nutritive components and MEBO components with biological activities can permeate into the deep layer of the wounds and give full play of its physiological and pharmacological effects to promote skin tissue regeneration and reparation. The whole process of burns wound regenerative reparation in situ is accomplished under FIM protection and by standard application of MEBT/MEBO. The microcirculation in the deep layer of the wound could only be regenerated as a physiological capillary tree frame under the protection of the FIM, so that nutritive materials could be transferred to the primitive skin blastemata and skin islands, which were regenerated in situ by stem cells and afterwards developed and expanded to heal the wounds. |
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