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What is the mechanism of BRT&MEBT MEBO technique (BRT&MEBT MEBO refers to Burns Regenerative Therapy & Moist Exposed Burns Technique/Moist Exposed Burns Ointment)?

BRT&MEBT/MEBO has such therapeutic effects in clinical burns treatment such as pain alleviation, prevention of progressive damage, prevention and controlling of infection, wound healing promotion and skin regeneration in situ & scarless healing of deep II degree and
superficial III degree burns wound.

Under the role of MEBO’s ingredients of medicine/nutrition associated with patented dosage form (see Q4, Part3) frame structure having breath-like function at wound, focusing the burns pathogenesis, MEBO has the following pharmacological effects.

1. Skin regeneration via cytokeratin19 positive skin stem cells; (see Q11, Part1)
2. Appropriate culture condition of the regeneration via stem cells in situ---Moisture (see Q14, Part1), Nutrition (see Q3, Part3), Micro-environment (see Q15, Part1)-
3. El inating/im preventing pathological course of local burn wound
  • Protecting wound to reduce capillaries leakage (water loss) and anti-shock [14-15] (see Q14, Part1)
  • Necrotic tissue removed without secondary injury on viable tissue (see Q16, Part1)
  • Stopping progressive necrosis (see Q17, Part1)
  • Anti-inflammation (see Q19, Part1)
  • Stopping the pain (see Q20, Part1)
4. Eliminating/preventing the factors resulting in secondary complication such as infection (see Q21, Part1)
5. MEBT-Assurance of full playing MEBO’s effects (see Q9, Part1)

Reference:
[14] ‘A Comparative Study on the Anti-shock Effect between MEBO and Dry-Exposed Burn Therapy Using a Rabbit Model’, Xu RX., Burns Regenerative Medicine and Therapy, 1st ed., ISBN 3-8055-7661-7, Basel: Karger; 2004. p. 47-50
[15] ‘Clinical Study on Invisible Water Loss of Burns Wounds Treated with BRT with MEBT/MEBO’, Xu RX., Burns Regenerative Medicine and Therapy, 1st ed., ISBN 3-8055-7661-7, Basel: Karger; 2004. p. 53-55
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