A tissue unit consists of more than one type of cells in human organs,
which exert one or more than one life functions in human lives.
Regenerative Nutritious Components:
Cell nutritious components in vivo and in vitro, which could activate
and maintain the process of cell proliferation and differentiation and
finally form tissue organs.
The damaged or necrotic cells in organs regenerate into live tissue
cells, tissues or organs in situ. This regeneration is not
transplantation of cells, tissue or organs from in vitro.
(Moist Exposed Burn Therapy/Ointment):
It was invented in the 1980s by Professor Rongxiang Xu. MEBO is a
botanic drug consisting of multiple botanic components and animal
nutritional ingredients cooperated with a unique patented sponge-like
frame structure dosage form to treat various (depth/TBSA/cause) burns,
wounds and ulcers in regeneration of skin organ.
The Chinese Burn Association of the Integration of Traditional and
Western Medicine (CBAIM) was officially founded on December 28,1996; it
is an independent, not-for-profit organization dedicated to stimulating
and supporting burn-related research, education, care, rehabilitation,
and prevention. Especially to worldwide spread and popularize the Burns
Regenerative Therapy, which is an innovation in burn care field,
proposed by Prof. Xu Rongxiang. To advance these goals, the CBAIM sets
up a national medical network with many burn centers and hospitals to
provide first aid service and medical supervision, sponsors a variety
of educational programs, fellowships, research, teaching and
From 1998, the CBAIM appraise about 10 Burn
Stars each year from numerous of depth burn patients, the total burn
body surface area of them all exceeded 90% and they were successfully
salvaged and cured with Burn Regenerative Therapy (BRT).
An undifferentiated cell found in a differentiated tissue that can
renew itself and (with certain limitations) differentiate to yield all
the specialized cell types of the tissue from which it originated.
Burns are classified according to the depth of the burn. In
partial-thickness burns some part of the stratum basale remains viable,
and regeneration of the epidermis occurs from within the burn area as
well as from the edges of the burn. Partial-thickness burns are divided
into first-and second-degree burns.
involves only the epidermis and are red and painful, and slight edema,
or swelling, can be present. They can be caused by sunburn or brief
exposure to hot or cold objects, and they heal without scarring in
about a week.
damage the epidermis and the dermis. If there is minimal dermal damage,
symptomas include redness, pain, edema, and blisters. Healing takes
about 2 weeks, and there is no scarring. If the burn goes deep into the
dermis, however, the wound appears red, tan, or white; can take several
months to heal; and might scar. In all second-degree burns, the
epidermis regenerates from epithelial tissue in hair follicles and
sweat glands, as well as from the edges of the wound.
full-thickness, or third-degree,
burns the epidermis and the dermis are completely destroyed, and
recovery occurs from the edges of the burn wound. Third-degree burns
often are surrounded by areas of first- and second-degree burns.
Although the first- and second-degree burn areas are painful, the
region of third- degree burn is usually painless because sensory
receptors in the epidermis and dermis have been destroyed. Third-degree
burns apear white, tan, brown, black, or deep cherry red.
partial-thickness and full-thickness burns
take a long time to heal, and they form scar tissue with disfiguring
and debilitating wound contracture. To prevent these complications and
to speed healing, skin grafts are often performed. In a split skin
graft the epdermis and part of the dermis are removed from another part
of the body and placed over the burn. Interstitial fluid from the burn
nourishs the graft until blood vessels grow into the graft and supply
it with nourishment. Meanwhile, the donor tissue produces new epidermis
from epith epithelial tissue in the hair follicles and sweat glands in
the same manner as in superfical second-degree burns.
Is the abbreviation of Burns Regenerative Therapy, established by
Professor Rongxiang Xu, is an innovative therapeutic system completely
different from the conventional burn management, both in concept and in
practice. This new approach is aimed at treating damaged tissue organs
in skin by potentiating and stimulating Potential Regenerative Cells
and Stem Cells in situ and thereby directly repairing and regenerating
tissues of the skin without transplantation.
A fluid that has exuded out of a tissue or its capillaries due to
injury or inflammation.
Primitive (undifferentiated) cells from the embryo that have the
potential to becomea wide variety of specialized cell types.
Literally, "in glass"; in a laboratory dish or test tube; an artificial
A Latin phrase meaning “in the original location.”
scientific experimentation, it refers to experiments conducted in the
actual site of the phenomenon under study, in contrast to in vitro
(outside the living body and in an artificial environment) and in vivo
(in the living body of a plant or animal).
Is the abbreviation of Moist Exposed Burn Therapy and Moist Exposed
Burn Ointment( a patented burn ointment), the revolutionary and
practical burn therapy invented by Prof. Xu Rongxiang, it consists of
two clinical system: the local treatment of burns wound and the
systemic treatment of burns. it contains series of theories and applied
techniques. Clinically, this therapy is carried out through MEBT and
regenerative cells (PRCs)
The special mature tissue cell discovered by Dr. Xu, which has the
potential ability to regenerate to a functional tissue similar as stem
cell but normally exists in tissue as a tissue cell. It can also be
called as the special differentiated tissue cell coming from
proliferating cell during different development stages in all types of
organs in the organism .
Cells with the ability to divide for indefinite periods in culture and
to give rise to specialized cells.
This technique is to apply specially made surgical instruments
“Plough Saw Blade” or operating knife, rolling
knife to cut
wound surface, forming scratch about 1mm in spacing and depth to
relieve the tension of degenerative and necrotic epithelial tissue;
help subdermal vascular plexus in circuit, initiate and activate PRCs
of residual skin tissue and regenerate skin organ in situ.
MEBO has good compatibility with burn wound exudates and can form a
fibrous isolation membrane in the course of wound necrotic tissue
liquefaction. The membrane is composed of lipoids produced by the
biochemical reactions of MEBO and lipoproteins complexes produced by
exudates of plasma protein from wounds. The membrane tightly covers the
wound surface, so that the neo regenerative stuff can attached to it
and the wounds can be repaired in a regenerative way in physiologically
MEBO has net-like frame form. It's composed by grease and surrounding
beeswax. There are abundant linoleic acids (belongs to non-saturation
acid), which can be decomposed with sterol stuff, aldehyde oxide, keton
oxide, lipid, adipoidand, etc. This process is called
“Three No principles” of MEBO application: no pain
on wounds, no bleeding and no injury to living tissues.
"Three timely principles" is one important principle in the management
of wounds; Timely removal of liquefied products, timely removal of
necrotic tissue and timely application of the drug (MEBO).
"Three no accumulation" is one important principle in the management of
wounds; no accumulation of necrotic tissue, no accumulation of
liquefied products and no accumulation of excessive drug (MEBO).