methods in Liquefaction period using MEBT/MEBO
After removal of liquefied
necrotic tissues, a
fibrous isolation membrane is formed on the wounds surface
like a layer of transparent cornea.
is very important to protect this membrane (to be explained later).
In clinical practices, wound necrotic tissue liquefaction
should be distinguished from wound
is a process that inflammation reaction is taking place in viable
tissues affected by pathogenic bacteria.
always brings on the purulence and necrosis of living tissues.
is always characterized by local
redness, swelling, fever,
pain and dysfunction.
a process that necrotic tissue under the action of MEBO is turned
automatically from solid state to liquid state and be removed without
causing any further damage. There is no living tissue involved
in this process.
Figure: On day4, the
wounds began to liquefy under the action of MEBO, and wound skin began
A layer of milky
milky yellow, homogeneous, fine and smooth semi-fluid substance is
formed on the wounds and is removed through changing of the dressings
without causing any damage.
The following principles should
A.Early application of the drug:
recommended to apply the drug within 4 hrs post injury.
The purpose is
to save the
tissues in the stasis zone of the wounds and prevent progressive
necrosis to ensure the efficacy of thie treatment.
B. The drug should be applied in the whole course
of the treatment without interruption:
No other drug or
treatment should be used to replace it in the whole course of
Dry therapy and
astringent drugs are forbidden.
is not allowed to apply directly on the wounds.
Don't use water
to wash the wounds.
C.Wound dressing change should be carried out in a
products should be removed every 4 hrs.
carefully, follow the "Three
don't cause any further damage in the normal skin tissue.
It is veiy
important to protect the fibrous isolation membrane to cover the
Adhere to the "Three DON'T principle"
so that physiological regenerative repair of the wound can be achieved.
D. Wound treatment:
"Three timely principles"
is one important principle in the management of wounds, i.e.
removal of liquefied products,
removal of necrotic tissue
timely application of the drug.
principle is "Three no
accumulation of necrotic tissue,
accumulation of liquefied products
no accumulation of excessive drug (MEBO).
In the treatment of large area burn wounds, it is
important to strictly follow the above principles not only to ensure
quick healing of the wounds, but also directly related to the systemic
condition and recovery of the patients.
This can help
reduce the amount of bacteria and
absorption of inflammatory and burn toxins produced in the necrotic
tissue and is the key to effective improvement of the systemic
condition and lessening of the symptom of intoxication.