Treatment for Third Degree Burns of BRT with
Third-degree burns are also an indication for BRT
As the epidermis and dermis of third-degree burn
wound are totally destroyed,
it is quite difficult to cure third-degree burns.
The conventional medical science for burns is
that third-degree wounds cannot heal spontaneously, and the only
solution is to use surgical skin grafting to close them.
The clinical study and administration of BRT with
MEBT/MEBO for curing third-degree burns wounds will be described in
The following is just a brief description of the
principle and method of this treatment.
Decompression of the deep tissues
- relieve any pressure caused by the necrotic
layer is of critical importance;
- protect the necrotic full-thickness skin;
- promote stem cells containing the skin
in subcutaneous tissue to regenerate and differentiate to form a skin
- culture the newly regenerated skin island while
liquefying and discharging the necrotic dermis;
- promote the skin island to spread and cover
subcutaneous tissue to form new skin;
- and help third-degree burns wounds heal
For third-degree wounds injured down to the muscle layer,
excise most of the necrotic tissue by surgical operation, liquefy and
discharge the rest of the necrotic layer with BRT with MEBT/MEBO, upon
which culture granulation tissue, then plant skin cells till the wound
closes and heals.
For wounds with bone exposed,
clean away the exposed outer soft tissue, drill holes on the bone
surface with a bone drill at intervals of 0.5–1 cm, deep into
medullary cavity of bone until bleeding. Apply MEBO to cover
wounds, and culture and support the growth of granulation tissue from
the holes. When the granulation tissue spreads to cover the bone surface, skin
grafting can be performed to close the wound, or the wound heals by
migration of epithelial cells from the wound edges.
The necrotic tissue of third-degree burns should
decompressed by cutting both horizontally and vertically at a 1 mm
tooth distance and depth with a specially designed method: ‘plough saw blade’.
Then apply MEBO for protection and clean away the exfoliated or
area third-degree burns, first of all apply MEBO to
protect wounds and then use 'plough
saw blade' to decompress necrotic skin.
Treat wounds complying with the method
area burns, apply the method mentioned above when the
patient is in stable vital signs.
1. Ill degree burn with area of 85%TBSA.The
pathological section at right side shows full-thickness skin necrosis.
2. Apply cultivating and tension relieving method
on III degree wounds on chest. Apply MEBT/MEBO to treat.
3. Clean liquefied necrotic tissues in time and
treat wounds complying with the principle of treating deep IIdegree
4. On 20th day postburn, burned necrotic tissues
are liquefied and discharged. A layer of membrane forms on wounds. The
pathological section shows that wounds were repaired by regenerative
5. Under the protection of MEBO and membrane,
regenerative skin tissues form dense skin islands.
6. Pathological section: stem cells regenerate and
repair skin in situ.
7. 'Skin islands' gradually extend to normal skin
8. On 49th day postburn, the pathological section
of healed skin shows structure of normal skin.
9 . On 7 2nd day postburn, whole layers of skin
regenerate, repair and heal.