Toxic epidermal necrolysis is a life-threatening skin disorder characterized by a blistering and peeling of the top layer of skin. 

This disorder can be caused by a drug reaction -- most often penicillin -- or another disease. About one-third of all diagnosed cases of toxic epidermal necrolysis are a result of unknown causes.
 

Toxic epidermal necrolysis can cause the skin to peel off in sheets, leaving large areas that look scalded. 

The loss of skin causes fluids and salts to ooze from the raw, damaged areas which can easily become infected. 

The following are the most common symptoms of toxic epidermal necrolysis.

However, each person may experience symptoms differently:

• a painful, red area that spreads quickly
• the top layer of skin may peel without blistering
• scalded-looking raw areas of flesh
• discomfort
• fever
• condition spread to eyes, mouth, and genitals

The symptoms of toxic epidermal necrolysis may resemble other dermatologic conditions.