It has been well established that vertebrates of lower species, particularly urodele amphibians (common called “salamanders”), have an intrinsic capacity to regenerate a variety of body parts, including limbs, tail, jaw, and retina.

In higher mammals, examples of complex tissue regeneration are less common but can be seen in the seasonal regrowth of deer antlers. 

For humans, there is description of distal fingertip regeneration in children, but not in fully developed adults. Thus, some concluded that regenerative potential declines with the evolution of complexity. See  review by Gurtner GC et al. (2007) Annu. Rev. Med.  58:299-312.

For an adult with a severed distal finger, the convention treatment generally includes surgical debridement of damaged tissue and suture of the residual tissues with the severed fingertip (if it can be retrieved) or direct closure of the wound (if the fingertip cannot be found or salvageable) to form a stump. Thus, this approach not only leads to scarring of the hand, but also results in reduction deformity and, more importantly, loss of physiological function of the finger.

The invention of MEBO's regenerative therapy completely changes such a grim picture and represents a major paradigm shift in this field. 

Consistent with the regeneration of functional skin organ of an adult, application of MEBO's regenerative therapy to human adult limb regeneration has produced groundbreaking clinical r esults. 

The clinical evidence collected from near a thousand cases shows that after treated with the MEBO regenerative therapy adult patients with severely damaged or lost limbs can recover with fingertips regenerated with normal physiological structure and function. 

Here are the clinical evidence.

Case 2: Paratelum Mutilation Wound of the Left Middle Finger End

Case 3: Paratelum Mutilation Wound of the Left Middle Finger and Ring Finger

Zhou, Male. 32 years old, the middle finger and the ring finger of the left hand were pricked by lathe and the patient entered Huangpu People's Hospital, Zhongshan City. After debridement, MEBO was used. Burn regenerative therapy was continued during the whole treatment course. The patient recovered 41 days later. The appearance and the function of the injured fingers recovered nearly thoroughly.

From above, application of MEBO's regenerative therapy to the treatment of lost or severely damaged fingers of adult humans could not only repair the wounds but also regeneration of fingers with normal structure and function, including bones, muscles, nerves, blood vessels, connective tissue, finger nails and skin.

These results demonstrate that the regenerative potential of adult humans is much stronger than previously expected. 

Consistent with what was observed for the regeneration of skin of burn patients, establishing an appropriate moist environment favoring regeneration and providing nutrients to the wound to stimulate and sustain the regeneration by cultivating stem cells in situ is the key to the success.

This regenerative therapy has been used for the last decade in China and 20+ other countries for treating a wide variety of wound, including severely damaged or lost limb as exemplified herein.

The key question is how this regenerative potential can be harnessed to enable repair and regeneration of the body in the face of injury, diseases and aging.

MEBO provides the answer to this question by developing uniquely combined and formulated botanical products which have been mass produced and reliably used to treat millions of patients for the last two decades.

The clinical evidence we obtained is not isolated and anecdotal, but results of decade-long practice of MEBO regenerative therapy invented by Dr. Rongxiang Xu.

The fact that the severely injured or lost limbs of adults can be regenerated with restoration of structure and function by using the MEBO regenerative therapy sheds new light onto regenerative medicine and creates a revolutionary scientific field centered on regeneration of functional human organs via cultivating stem cells in situ and in vivo. 

Application of human regeneration in medical technology, so that finger (toe) the success of renewable sources of recovery, following the wet renewable technology enables deep burn skin regeneration in situ after recovery, once again to verify in situ regeneration of the somatic cell tissues, organs clinical success, and further proves that renewable technology in the human body tissue and organ damage must have a scientific basis for the three aspects. 

Namely: 

1, regeneration of life (potential regenerative cell); 

2, the lives of renewable material - the exclusive use of MEBO MEBO products; 

3, life regeneration of the environment - norms of human tissues and organs in situ regeneration technology (therapy). 

MEBO let finger (toe) renewable recovery cases, including the human body (meaning, toe) in the bone, muscle, skin, tendons, subcutaneous fat and fascia, blood vessels, nerves and sweat glands, sebaceous glands, nails and other skin subsidiary organ such as embryonic development in the ectoderm, mesoderm organizations regeneration in situ recovery. 

Fully verify the application of renewable as long as the norms of the whole nutritional substances, in accordance with the norms of human regeneration technology implementation, more than can be achieved in human tissues and organs in situ regeneration of recovery, and restore the organ morphology and function.

According to national health care network in Shandong, Guangdong, Sichuan Medical Center reported that the application of human tissue and organ regeneration in situ technology allows finger (toe) the success of renewable sources of recovery of clinical cases have been over 3000 cases, the current headquarters in Beijing is continuing off refers to renewable sources of clinical cases to observe the norms of treatment has been made very good clinical results.

According to the clinical experience, finger renewable conventional treatment is as follows: 

Conventional treatment

The surrounding normal skin conventional disinfection and cleaning, the prohibition on wound debridement and disinfection carried out, only bar-line arterial bleeding, if tear the organization, can be connected suture, and then directly coated with MEBO, using the closed wound, Mr amount to more than . 

Then used Meibao速愈paste wound dressing, half an hour to replace drug-coated and implement MEBT treatment, about four hours to replace a MEBO. Every morning, no damage directly a wound on the clean-up of sediment, continue to use MEBO MEBT line treatment, renewable until the completion of severed fingers. Clean-up of sediment from the wound when the wound avoid injury to non-bleeding, not pain. 

According to the wound healing process of the appearance of change (as shown), during different periods of time, relatively different wounds, regeneration need to wet the basic principles of Regenerative Therapy, in the dressing obtained in the course of the "three principles should not be" that is, no pain, not bleeding, not to continue the operation of normal tissue injury to the dressing was changed. 

After treatment, the wound basal clear, granulation tissue ruddy fresh, delicate, showing granular, clinical performance for the wound to form a protective layer-like cover, norms formation after administration wound, skin, skin, bone tissue regeneration complete synchronization finger wound rehabilitation, skin and nail to reach the annex, including the effects of recovery.

Systemic treatment
Significantly contaminated wounds of patients, routine use of tetanus antitoxin (TAT) 1500u skin test negative after the intramuscular injection of staining serious wound or injury for more than eight hours, then injected 3000u.

According to hospital after infection reported by subjects, as well as the prevalence of bacteria in patients with previous use of antibiotics in general choose to penicillin or clindamycin category intramuscular or intravenous injection.

For fresh wound debridement adequate use of pre-1st, and then 5-7 days of continuous drug use.