According to the pathogenic process of superficial second-degree burns, the treatment can be carried out in two stages.

1. First Stage.

Treatment in the early stage – the period from emergency treatment postburn to the end of shock period (within 3–4 days after injury). 

The clinical signs in this stage include pain, edema, blisters, and a great amount of blood plasma exudated from the site where blister skin exfoliates. 

According to the principle of BRT with MEBT/MEBO, apply MEBO directly all over the wound, puncture the blister (if present) on the lower part to discharge liquid. 

Do not remove the blister skin, directly apply MEBO on the blister skin 3–4 times daily. 

With the application of MEBO, a layer of thin soft membrane forms upon the wound free of blister skin, the membrane still allows the exudates to ooze through, and then it gradually thickens. 

Do not remove the soft membrane, since it can substitute the skin role of fulfilling breathing and protection. 

Continue MEBO application directed by BRT.

2. Second Stage.

It is the wound-repairing period when the shock stage ends and the residual viable epidermis tissue begins to regenerate and recover, usually lasting 3–4 days.

In this period, the basal cells in the epidermis recover to form a granular layer and thus promote wound healing. 

In clinical treatment of BRT with MEBT/MEBO, after the edema period, the blister skin loosens and exfoliates, and the thin soft membrane formed on the wounds also loosens and exfoliates. 

Simply cleaning away the blister skin and soft membrane is first desired, then continue the application of MEBO to protect the regenerated wounds till healing. 

During the whole treatment, neither pain nor further injury to wounds is allowed. 

The correct application method helps the wounds heal without causing any infection, pain, scar formation or hyperpigmenta-tion. 

Generally, superficial second-degree wounds treated with BRT with MEBT/MEBO heal within 6–8 days and the skin recovers completely to its normal physiological status within 3 months.

Apply MEBO directly on wounds in 4 hours postburn. 

The thickness of medicine should not be thicker than 1mm and redress the wounds eveiy 4-6 hours. 

Clean residues on wounds and exudates with disinfectant gauze before redressing each time. 

Generally, wounds will heal in 6-7 days. 

For wounds with blisters, release water in blisters at low position and do not remove the blister skin. 

Remove the blister skin 3-4 days postburn and continue applying MEBO.

Seven days later, wounds wound heal.

1. Apply MEBO with thickness   less   than 1 mm.

Release water in blisters at low position and do not remove the blister skin.

9. Seven days later, wounds would heal. Apply MEBO as a protective ointment for 7-10 days so as to restore normal skin function.