MEBO MOIST EXPOSED BURN OINTMENT (MEBO) safe quick no-pain no-scar for Burn Wound 40g

Main Ingredients:

Radix Scutellariae, Cortex Phellodendri Chinensis, Rhizoma Coptidis, Beeswax, and Sesami oil

Product Description:

Light yellow-brown ointment with sesame oil smell

Functions and Indications:

• Clear away heat and toxic materials, subside swellings, relieve pains and promote granulation;
• analgesic, anti-inflammation, anti-infection, ulcer-management, liquefying and removing necrotic skin tissues without causing further injury,
• physiological regeneration and repair of skin,
• promoting the wound healing, mitigating injuries
• and lessening scar formation.

Applications:

1. Acute Wounds

• Burn wounds including first degree, superficial second-degree, deep second-degree superficial type, deep second-degree deep type, superficial third-degree,and deep third-degree burn wounds, burn wounds on bone, electronic burns and severe chemical burns
• Surgical wounds including donor site wounds, cosmetic surgical wounds, ostomy wounds, wounds of circumcision, obstetrical wounds
• Pressure wounds
• Amputated limbs

2. Chronic Wounds (Typical Clinical Cases Profiles)

• Diabetic ulcers
• Pressure ulcers (Bedsore)

  Soft tissue necrosis
• Chemotherapeutic phlebitis
• Radioepidermitis
• Herpes zoster
• Newborn diaper dermatitis
• Common warts  

Mechanisms 

• Regeneration of skin organ in situ after deep burns via keratin-19 positive expressed epidermis stem cells;
• Analgesic effects by protecting nerve endings and relaxing arrectors pilorum;
• Wound protection by a unique sponge-like frame structure dosage form, which creates a physiological moist environment to keep the barrier function of burn wound in early stage;  
• Anti-inflammatory by the effects of ß－sitosterol and other ingredients;
• Stop or reduce progressive necrosis by recovery of stasis zone in burns wounds;
• Drainage of necrotic tissues without further injury to residual viable tissues;
• Prevention and control of wound infection through variation of pathogenic microorganism and reduction in bacterial toxicity on burn wounds and necrotic tissue liquefaction and removal.

Precautions

1. Patients suffering larger burn surface areas and developing systemic disease must be treated by the doctors of in the hospital with experiences of MEBT. 
2. Repeated squeezing and crashing may soften and thin the ointment, especially in summer, which will not affect its therapeutic efficacy. When it occurs, soak the screwed-tube in boiling water for several minutes and then stand to cool, its dosage form will return to normal. 

Adverse Effects:

No adverse effect has been reported.

Direction for Use:

For external use only. Directly apply MEBO ointment onto the burn or scald wounds to a thickness less than 1mm every 4-6 hours. Remove the residual ointment and exudation before medicine renewal.The wound should be exposed. 

For first aid at home (kitchen), immediately apply MEBO on the wounds to relieve pains, arrest bleeding, alleviate injuries and prevent from infection in case of scalds and burns by hot oil or boiling water.  The effect is the sooner the better.  The consequent treatment of wounds should be conducted according to the following specific cases.

For First-degree burns:

The clinical signs of first-degree burns include skin redness, slight swelling and pain. Immediate application of MEBO may relieve the pain. The erythema gradually diminishes as MEBO is warmed in situ and absorbed through the skin. At 12h postburn, the skin may return to normal. For burns with edema, the epidermis is partially destroyed, the pains may be relieved more slowly and the wounds would heal in 2~4 days when the superficial stratum corneum exfoliates.

1. I degree burn, skin redness, slight swelling and pain

Apply MEBO immediately postburn. With the absorption of MEBO, pain is relieved and edema fades away gradually. Continue applying MEBO.
Two to three days later, burned skin would heal. Continue apply MEBO as a protective ointment for about one week so as to fully restore normal skin functions.

2. Treatment for superficial second-degree burns:
Apply MEBO directly on wounds in 4 hours postburn. The thickness of medicine should not thicker than 1mm and redress the wounds every 4-6 hours. Clean residues on wounds and exudates with disinfectant gauze before redressing each time. Generally, wounds will cure in 6-7 days. For wounds with blisters, release water in blisters at low position and do not remove the blister skin. Remove the blister skin 3-4 days postburn and continue applying MEBO. Seven days later, wounds wound heal.

(1). Apply MEBO with thickness less than 1mm. Release water in blisters at low position and do not remove the blister skin.
(2). Three to four days later, remove the blister skin and apply MEBO immediately. Smear MEBO along the direction of fine hair gently to relieve stimulations.
(3). Four to six hours after applying MEBO, a layer of white liquefied exudates was formed. It is a normal phenomenon of excreting necrotic skin tissues (Do not take it as infection).
(4). Clean the liquefied products with no injury. Redress MEBO with no pains, bleeding or damage to live tissues on wounds.
(5). Alternatively, use disinfected gauze to absorb liquefied products for 30 seconds or 1 minute.
(6). Disclose gauze along tangential direction.
(7). Clean the liquefied products completely.
(8). Smear MEBO evenly on wounds. The thickness is less than 1mm.
(9). Seven days later, wounds would heal. Apply MEBO as a protective ointment for 7-10 days so as to restore normal skin function.

MEBO for Local Burn Wound Treatment

Systemic Treatment -- MEBT

Video about MEBO for Burn:

superficial II Degree Burns Mixed with Deep II Degree Burns (A one and hale-year-old girl was scaled by boiling water with 30% TBSA)

Storage:

Store the ointment in acool place, keep out of reach of children

Date of Production:

show on outer package

Shelf Life:

3 years

Case about MEBO for Burn

1. Newsweek 1990 May 7, A Simpler Way to save lives

Patent 

• “Pharmaceutical Composition for Treating Thermal Injuries of Warm Blooded Mammals Including Humans” US Patent No.: 5,405,608
• “Pharmaceutical Base and the Use of the Base” US Patent No.: 5,817,322
• European Patent No.: 0606786/0763362
• Japan Patent No: 3065530/3126583

MEBO MOIST EXPOSED BURN OINTMENT (MEI BAO SHI RUN SHAO SHANG GAO) in 1 tube/box,manufactured by MEBO International Group, one of the dominant research base of stem cell, organ regeneration and human cell energy, and manufacture base of Regenerative Medicine for human tissue organs in China

MEBO MOIST EXPOSED BURN OINTMENT

(MEI BAO SHI RUN SHAO SHANG GAO)

Most Frequently asked Questions regarding MEBO Moist Exposed Burn Ointmet?

1. What are the key points and first-aid measures on the fire spot?
Burn is a common lesion among fire accidents in industrial production and family accidents. Several points should be noted in the rescue more

2. What are the characteristics of child burn and how to do first aid?
Child burn (scald) is common in daily life, which is also the accident worrying young parents and seniors the most.  more

3. How to judge the depth of the burn wound?
The depth of burn and scald wound is divided to the following three degree and six division type, which are: first degree, superficial second degree, deep second superficial type, deep second deep type, superficial third degree and deep third degree.  more

4. How to calculate burn area?
one more simple method: the area of the patient’s palm occupies 1% of body surface area. more

5. MEBO solve the four technical difficulties in treating burns?
The four difficulties during burn treatment are: pain, infection, progressive necrosis and scar formation for deep second degree burn wound.  more

6. What should be paid attention to during local treatment of burn by MEBT?
For middle and small area burn and scald wound, the treatment can be operated in common wards.

For small area burn, the treatment can also be operated in family. But the important thing is: the room should be clean with suitable temperature (above 26 degree) and the humidity of above 60%.

Wound becoming dry and forming scabs should be prevented. more

7. How to treat burn correctly at home by clinical manifestation of burn wound?
Measure of diagnosis and estimation of burn depth has been introduced before, but how to estimate the depth of burn and treat it in daily life.

A simple method could be applied.

Three types of burn could be observed at early stage of burn: erythema, blister and eschar as will be described respectively in the following pieces. more

8. Why is water or normal saline not recommended to clean wounds during MEBT/MEBO treatment?
water (especially cold water) is another stimulating factor, which can lead to local vasoconstriction, microcirculation stasis, etc..  more

9. Are antiseptics or antibiotics needed in MEBT/MEBO dressing change?
Antiseptics can cause damage to the residual viable cells (including potential regenerative cells) in parbiosic tissues of the wound during sterilization, therefore it is not recommended to use antiseptics on the wound by MEBT/MEBO.

In addition, any antibiotics are not allowed on the wound either, in order to avoid the generation of drug resistant bacteria population in the affected part, which has attained the consensus of the international medical burns field.

10. Can the infected wound (including infected surgically operative incision ) be treated with MEBT/MEBO and How to change dressing?
MEBT/MEBO has significant effect of liquefying necrosis, smoothing drainage, prohibiting the growth and proliferation of bacteria and promoting wound healing.

It can be applied to infected wound to control the infection and promote wound healing.

For severely infected wound with abnormal temperature and WBC value and without obvious improvement of the systemic symptoms after the local treatment, combined therapy should be applied such as sensitive antibiotics by oral administration or injection to control infection, combined with nutrition supply and integrated treatment to improve the general immunity.

MEBT/MEBO can also be applied to infected surgically operative incision.
11. Can climactic conditions affect MEBO efficacy and what are the optimal temperature and humidity required by BRT&MEBT/MEBO?
Yes, they can.

Because 26 ~30 ℃ is the optimal temperature for the clinical application of MEBT/MEBO to liquefy and discharge the necrotic tissues on the wound and regenerate new skin in situ with the optimal relative humidity above 60%.

In natural condition, moist and warm environment is suitable for the application of MEBT/MEBO;

otherwise method of creating artificial condition by air-conditioner, burns healing instrument, warmer, humidifier and counterpane should be adopted to obtain the optimal ambient temperature and humidity.

12. Is immersion bath or shower allowed for burns patient treated with MEBT/MEBO?
For extensive burns patient treated with MEBT/MEBO, immersion of the wound is not allowed during the treatment in principle, since water and disinfectant will damage tissue cells of the wound, which is unfavorable for regenerative wound healing.

For healed wound or wound with small area unhealing (the unhealing wound should be well protected from water), shower is allowed with the use of bland neutro-bathfoam; or just wash the normal skin.

13. Why is it necessary to continue applying MEBO for 10-15 days after burns wound healed by MEBT/MEBO?
In early stage of burns wound healed with MEBT/MEBO, newly-regenerated skin has not restored its normal function completely, i.e.

• epidermal tissue needs further physiologic adjustment and metabolism,
• sebaceous gland needs going through the course of metabolic compensation,
• excretory tube of sweat gland is still blocked
• and function of skin chromocytes can not meet the requirement of normal skin.

Therefore, MEBO should be applied continuously as skincare cream for 10-15 days in this stage.

For deep burns wound, MEBO SCAReducer is recommended for 1-3 months after healing, in order to accelerate the restoration of skin function.

14. MEBO consumption amount and Period of healing?

• For patients with 1% TBSA(Total Burn Surface Area), the drug consumption amount for each application is about 10 grams, so the day consumption amount is about 40 grams (1 tube) for patients changing dressing for 4 times.
• For patients with TBSA≤10%, the consumption amount is about 20 tubes. For patients with TBSA between 10% and 30%, the amount is about 60 tubes.
• For patients with TBSA between 30% and 50%, the amount is about 250 tubes.
• For patients with TBSA larger than 50%, the amount is more than 500 tubes.

The healing time

• For first degree burn is about 2 to 3 days.
• For superficial second degree burn, the healing time is about 7 days.
• For deep second degree burn, the healing time is about 20 days.
• For superficial third degree burn, the healing time is about 50 days.
• For deep third degree burn, the healing time is about 70 days.

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